New universal coronavirus vaccine may help prevent future pandemics – News Vibe24

    New universal coronavirus vaccine may help prevent future pandemics - Times of India
    Washington: Scientists have developed a universal vaccine that protects mice not only against Covid-19 but also other coronaviruses, while activating the immune system to fight a dangerous variant.
    Although no one knows what virus could cause the next outbreak, researchers at the University of North Carolina (UNC) in the United States have noted that coronaviruses remain a threat after the 2003 SARS epidemic and the global Covid-19 pandemic.
    To prevent a future coronavirus pandemic, the team designed the vaccine to provide protection against the current coronavirus SARS-CoV-2 and a group of coronaviruses known to make the leap from animals to humans.
    The study, published in the journal Science, looked at a second-generation vaccine: one that targets carnivores.
    Sarbecovirus, part of the large coronavirus family, is a priority for virologists, as two have caused catastrophic diseases over the past two decades: SARS and Covid-19.
    The group’s approach began with prophylactic mRNA, which is similar to the Pfizer and Moderna vaccines currently in use.
    However, instead of including the mRNA code for a single virus, they bind the mRNA from many coroners.
    When administered to mice, the hybrid vaccine produced effective neutralizing antibodies against multiple protein spikes – which viruses attach to healthy cells – including one associated with the B.1.351 variant, first detected in South Africa.
    “The vaccine has the potential to prevent outbreaks when used as a new variant,” said study lead author Ralph Baric, an epidemiologist at the UNC Gillings School of Public Health.
    The research includes data from mice infected with SARS-CoV and related coronaviruses, and the vaccine prevented infection and lung damage in mice.
    Additional tests could lead to clinical trials in humans next year, the researchers said.
    “Our findings are promising for the future because they suggest that we can design more universal pan-Qur’anic vaccines to prevent viruses that we know are at risk of spreading to humans,” said another lead author, David Martinez. School of Global Public Health.
    “With this strategy, we might be able to prevent a SARS-CoV-3,” Martinez said.

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